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David A Tess Selected Research

ketohexokinase

7/2022Transporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, A First-in-class Ketohexokinase Inhibitor for Metabolic Disorders and Non-alcoholic Fatty Liver Disease.
1/2022Effect of a Ketohexokinase Inhibitor (PF-06835919) on In Vivo OATP1B Activity: Integrative Risk Assessment Using Endogenous Biomarker and a Probe Drug.

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David A Tess Research Topics

Disease

2Obesity
07/2022 - 09/2007
2Non-alcoholic Fatty Liver Disease
07/2022 - 10/2020
1Type 2 Diabetes Mellitus (MODY)
07/2022
1Alcoholic Fatty Liver
07/2022
1Fatty Liver
01/2022
1Crystalluria
01/2020
1Hypertrophy
01/2017
1Diabetic Nephropathies (Diabetic Nephropathy)
01/2017
1Proteinuria
01/2017
1Fibrosis (Cirrhosis)
01/2017

Drug/Important Bio-Agent (IBA)

2ketohexokinaseIBA
07/2022 - 01/2022
2Pharmaceutical PreparationsIBA
01/2022 - 01/2020
1FructoseIBA
07/2022
1EnzymesIBA
07/2022
1Peptides (Polypeptides)IBA
01/2022
1AnionsIBA
01/2022
1Acetyl-CoA CarboxylaseIBA
10/2020
1Protein Isoforms (Isoforms)IBA
01/2017
1Blood Glucose (Blood Sugar)IBA
01/2017
1Biomarkers (Surrogate Marker)IBA
01/2017
1Ramipril (Altace)FDA LinkGeneric
01/2017
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
01/2017

Therapy/Procedure

2Therapeutics
01/2017 - 09/2007